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Case of the Week 277



What's the most likely diagnosis?

  • 63 year-old male with fever

  1. Silicosis
  2. Bronchoalveolar cell carcinoma
  3. Miliary tuberculosis
  4. Rheumatoid nodules
  5. Multiple arteriovenous malformations


Answer:

 


3. Miliary tuberculosis

 

 

More (Click Discussion Tab)


Miliary Tuberculosis

General Considerations

  • Widespread hematogenous dissemination of Mycobacterium Tuberculosis
  • So named because the nodules are the size of millet seeds (1-5mm with a mean of 2 mm)
  • Miliary TB represents only 1-3% of all cases of TB
  • Older men, African Americans and pregnant women are susceptible
  • Considered to be a manifestation of primary TB–although clinical appearance of miliary TB may not occur for many years after initial infection
  • When treated, clearing is frequently rapid
    • Miliary TB seldom, if ever, produces calcification
  • Under age 5, there is an increased risk of meningitis

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