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Gastric Polyps

• Most common benign gastric tumor

• Associated with:

            ∆ Hyperacidity+ulcers

            ∆ Chronic atrophic gastritis

            ∆ Gastric carcinoma

• Low incidence of malignant transformation

Hyperplastic polyp=inflammatory polyp (75-90%)

            • Proliferated gastric mucosa+inflammatory cells

            • Associated with pernicious anemia

            • Random distribution in stomach

            • Usually multiple polyps

            • Usually <1cm with no progression

Adenomatous polyp (10-20%)

            • True neoplasm with very low malignant potential

            • Associated with Gardner’s syndrome, coexistent gastric ca

            • Occurs more commonly in antrum

            • Often single

            • Usually>1.5cm in size

            • Occur in patients over 50 years old

Hamartomatous polyp (rare)

            • Densely packed gastric glands

            • Associated with Peutz-Jeghers syndrome

            • Usually <2cm in diameter

Retention polyp (rare)

            • Dilated cystic glands

            • Associated with Cronkhite-Canada syndrome

Villous polyp (rare)

            • Can undergo malignant transformation

DDX:

            • Menetrier disease (antrum is spared)

            • Eosinophilic polyps

            • Lymphoma

            • Carcinoma

            • Pancreatic rest (antrum)

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