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Cathartic Colon
• Prolonged use of irritating stimulant-type laxatives results in neuromuscular incoordination from chronically increased muscle activity • Usually requires 15 years or more of laxative use Agents • Cascara • Castor oil • Senna • Phenolphthalein • Podophyllum • Aloin Location • Usually involves colon proximal to splenic flexure-i.e...... predominantly right colon X-ray • Effaced mucosa with smooth, flattened surface • Absent haustrations • Pseudostrictures-smoothly tapered areas of spasm • Poor evacuation of barium • Patulous ileocecal valve • May have shortening of right colon DDx • Ulcerative colitis-except that rectum is spared in cathartic colon and there are no pseudopolyps or ulcerations
WH/93
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