Aortic Dissection
· Predisposing factors
o Hypertension (most commonly)
o Atherosclerosis
o Cystic medial necrosis
§ Marfan’s syndrome
o Coarctation of the aorta
o Aortic stenosis
o S/P prosthetic aortic valve
o Trauma (rare)
o Pregnancy (rare)
· Aneurysm defined by size criteria
o In general, ascending aorta > 5 cm
o Descending aorta > 4 cm
· Vessels involved with dissection
o Any artery can be occluded
o Usually the right coronary and three arch vessels are involved
with arch aneurysms
o Right pulmonary artery and left-sided pulmonary veins may be
occluded
· Types
o DeBakey Type I
§ Involves entire aorta
o DeBakey Type II
§ Least common
· Ascending aorta only
o DeBakey Type III
§ Most common
· Descending aorta only
o Stanford Type A
§ Ascending aorta involved
· Over half develop aortic regurgitation
o Stanford Type B
§ Ascending aorta NOT involved
· Most dissections arise either just distal to the aortic valve
or just distal to aortic isthmus
· True versus false channel
o False channel usually arises anterior in the ascending aorta
and spirals to posterior and left lateral in descending aorta
o True channel is usually larger
o Slower flow in false channel on MR
DeBakey Classification |
Stanford Classification |
Portion of Aorta Involved |
Common causes |
RX |
DeBakey Type I |
Stanford Type A
(ascending aorta involved) |
Involves entire aorta |
Hypertension
Atherosclerosis |
Usually surgically* |
DeBakey Type II
(least common) |
Stanford Type A
(ascending aorta involved) |
Ascending aorta only |
Cystic medial necrosis
e.g.Marfan’s
Ehlers-Danlos |
Usually surgically* |
DeBakey Type III
(most common) |
Stanford Type B |
Descending aorta only |
Hypertension
Atherosclerosis |
Usually medically |
*Goal is
to prevent backward involvement of the aortic valve or rupture into
pericardium
· Clinical
o Sharp, tearing, intractable chest pain
o Murmur or bruit of aortic regurgitation
o Previously hypertensive, now possible shock
o Asymmetric peripheral pulses
o Pulmonary edema
· Imaging Findings
o Chest films
§ Mediastinal widening
§ Left paraspinal stripe
§ Displacement of intimal calcifications
§ Apical pleural cap
§ Left pleural effusion
§ Displacement of endotracheal tube or nasogastric tube
o MRI
§ Intimal flap
§ Slow flow or clot in false lumen
o CT
§ Intimal flap
§ Displacement of intimal calcification
§ Differential contrast enhancement of true versus false lumen

CT of abdominal aorta shows intimal flap (dark line -red arrow)
with true lumen anteriorly and false lumen posteriorly
o Angiography
§ Intimal flap
§ Double lumen
§ Compression of true lumen by false channel
§ Increase in aortic wall thickness > 10 mm
§ Obstruction of branch vessels
· Diagnosis
o MRI if available is usually best for imaging ascending aorta
o Contrast-enhanced CT can image arch and descending aorta
o Transesophageal ultrasound, if available, especially for root
and ascending aorta
o Angiography
· Prognosis
Timing |
Death |
Immediate |
3% |
Within 24
hours |
20-30% |
By end of
1st week |
50% |
By 3 weeks |
60% |
By 3
months |
80% |
Alive at 1
year |
10-20% |