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CREST Syndrome


  • More benign variant of scleroderma

  • Consists of

    • Calcinosis

      • Calcinosis circumscripta

        • Usually of hands

    • Reynaud’s phenomenon

    • Sclerodactyly

    • Telangiectasias

      • Telangiectasias arise only on skin or mucous membranes of upper extremities or mouth

      • Telangiectasia is uncommon in scleroderma

  • Internal organ involvement, except for GI, is less common in CRST