· Fluid-filled cysts of the parietal pericardium consisting of a single layer of mesothelial cells
· Usually discover at age 30-40 years, predominantly in males (3:2)
· Most are asymptomatic and incidental findings
· Atypical chest pain can occur
· They are usually (75%) located at the cardiophrenic angle almost always on the right (3:1)
o DDX of a right cardiophrenic angle mass
§ Pericardial cyst
§ Sequestration
§ Foramen of Morgagni hernia
· They can occur higher and may extend into major fissure
o Classically they are soft and can be flattened on the edge that faces the fissure
· They rarely occur in the mediastinum
· Imaging findings

Pericardial Cyst. Frontal and lateral views of the chest demonstrate a mass at the right cardiophrenic angle with rim-like calcification that indicates the calcification has formed in the wall of a hollow viscus. This is a characteristic location for a pericardial cyst, which is calcified in this case.
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o Sharply marginated
o Round or oval mass
o From 3-8 cm in size usually
o They can change in size and shape with respiration or body position
o Rarely calcify
· On CT, their attenuation values of 20-40 HU, occasionally higher